CCTG

IND234

NCT03385655

IND234

Prostate Cancer Biomarker Enrichment and Treatment Selection (PC-BETS) Study

Status:

Recruiting

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II

Phase

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2nd+

Line of Therapy

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Any Stage

Disease Stage

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Biomarker(s)

MET, WEE1

Investigational

Product

Mixed

Treatment Arms

o WEE-1 inhibitor

o cMET inhibitor

o novel non-steroidal androgen receptor (AR) antagonist

o CFI400945 PLK4 inhibitor

o Ipatasertib AKT inhibitor

o Durvalumab and Tremelimumab immunotherapy

o Carboplatin platinum based chemotherapy