CCTG

CO.27

NCT02967289

CO.27

A Phase III, Randomised, International Trial Comparing mFOLFIRINOX Triplet Chemotherapy to mFOLFOX for High-risk Stage III Colon Cancer in Adjuvant Setting

Status:

Recruiting

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III

Phase

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Adjuvant

Line of Therapy

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Advanced / Metastatic

Disease Stage

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Biomarker(s)

N/A

Investigational

Product

Irinotecan

Topoisomerase I inhibitor

Treatment Arms

Experimental Cohort 1:
o Arm A: Tesetaxel + Nivolumab
o Arm B: Tesetaxel + Pembrolizumab
o Arm C: Tesetaxel + atezolizumab

Experimental Cohorts 2 & 3:
o Tesetaxel