
7465-CL-0301
NCT03474107
JCP043
A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer (EV-301)
Status:
Closed to Accrual

III
Phase

3rd
Line of Therapy

Advanced / Metastatic
Disease Stage

Biomarker(s)
Nectin4
Investigational
Product
Enfortumab Vedotin
Antibody‒Drug Conjugate (i.v.)
Treatment Arms
o Arm A: Enfortumab Vedotin
Participants will receive enfortumab vedotin (EV) on days 1, 8 and 15 of each 28 day cycle.
o Arm B: chemotherapy
Participants will receive the assigned drug (docetaxel, vinflunine or paclitaxel) on day 1 of every 21 day cycle.